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Din sökning på "*" gav 123677 sökträffar

Contextualizing selection bias in Mendelian randomization: how bad is it likely to be?

Selection bias affects Mendelian randomization investigations when selection into the study sample depends on a collider between the genetic variant and confounders of the risk factor–outcome association. However, the relative importance of selection bias for Mendelian randomization compared with other potential biases is unclear. New publication in International Journal of Epidemiology.Read more

https://www.lupop.lu.se/article/contextualizing-selection-bias-mendelian-randomization-how-bad-it-likely-be - 2025-09-29

Barriers and Opportunities for Use of Patient Registries in Medicines Regulation

The European Medicines Agency (EMA) established the Patient Registry Initiative to explore ways of supporting the use of patient registries in generating high-quality data for regulatory decision making and to enable a systematic approach to their use. We review barriers and opportunities for using patient registries in medicines regulation. A key aspect is that early discussions between all parti

https://www.lupop.lu.se/article/barriers-and-opportunities-use-patient-registries-medicines-regulation - 2025-09-29

Bayesian Methods for Exposure Misclassification Adjustment in a Mediation Analysis

Soil-transmitted helminth infections have been found to be associated with child development. The objective was to investigate hemoglobin levels and malnutrition as mediators of the association between Ascaris infection and intelligence quotient (IQ) scores in children. New publication in Epidemiology.Read more here.

https://www.lupop.lu.se/article/bayesian-methods-exposure-misclassification-adjustment-mediation-analysis - 2025-09-29

Nya utlysningar från VR

Följande utlysningar från Vetenskapsrådet är nu öppna Exploratory workshops inom utbildningsvetenskapProjektbidrag inom naturvetenskap och teknikvetenskapProjektbidrag inom utbildningsvetenskapNätverksbidrag inom utbildningsvetenskapProjektbidrag inom utvecklingsforskningNätverksbidrag Swedish Research LinksInternationell postdok inom utvecklingsforskningEtableringsbidrag inom naturvetenskap och t

https://www.lupop.lu.se/article/nya-utlysningar-fran-vr-0 - 2025-09-29

The Chinese National Twin Registry: a ‘gold mine’ for scientific research

The Chinese National Twin Registry (CNTR) currently includes data from 61 566 twin pair from 11 provinces or cities in China. Of these, 31 705, 15 060 and 13 531 pairs are monozygotic, same‐sex dizygotic and opposite‐sex dizygotic pairs, respectively, determined by opposite sex or intrapair similarity. Read more here.

https://www.lupop.lu.se/article/chinese-national-twin-registry-gold-mine-scientific-research - 2025-09-29

Glossary of health equity in the context of environmental public health practice

This Glossary, rooted primarily in the Canadian context but drawing on lessons from elsewhere, describes environmental public health regulatory practice in relation to health equity, including approaches that practitioners can use to contribute to addressing the social determinants of health. Read more here.

https://www.lupop.lu.se/article/glossary-health-equity-context-environmental-public-health-practice - 2025-09-29

Patient Registries in Idiopathic Pulmonary Fibrosis

Over the past decade, several large registries of patients with idiopathic pulmonary fibrosis (IPF) have been established. These registries are collecting a wealth of longitudinal data on thousands of patients with this rare disease. The data collected in these registries will be complementary to data collected in clinical trials because the patient populations studied in registries have a broader

https://www.lupop.lu.se/article/patient-registries-idiopathic-pulmonary-fibrosis - 2025-09-29

Rationale and Design of the Hamburg City Health Study

The Hamburg City Health Study (HCHS) is a large, prospective, long-term, population-based cohort study and a unique research platform and network to obtain substantial knowledge about several important risk and prognostic factors in major chronic diseases. A random sample of 45,000 participants between 45 and 74 years of age from the general population of Hamburg, Germany, are taking part in an ex

https://www.lupop.lu.se/article/rationale-and-design-hamburg-city-health-study - 2025-09-29

Should “garbage in–garbage out” be replaced by “little in–little out”? Questionnaire response rates need to be improved in surgical quality registries!

Surgical quality registries are important tools for both performing research and improving clinical practice. The Swedish National Knee Ligament Registry (SNKLR) has collected patient-reported and surgical data on more than 90% of the anterior cruciate ligament (ACL) reconstructions in Sweden. There has year-by-year been an increasing number of publications using data from SNKLR and the Scandinavi

https://www.lupop.lu.se/article/should-garbage-garbage-out-be-replaced-little-little-out-questionnaire-response-rates-need-be - 2025-09-29

Bias from self selection and loss to follow-up in prospective cohort studies

Self-selection into prospective cohort studies and loss to follow-up can cause biased exposure-outcome association estimates. Previous investigations illustrated that such biases can be small in large prospective cohort studies. The structural approach to selection bias shows that general statements about bias are not possible for studies that investigate multiple exposures and outcomes, and that

https://www.lupop.lu.se/article/bias-self-selection-and-loss-follow-prospective-cohort-studies - 2025-09-29